CAY10723 is an inhibitor of protein arginine deiminase 2 (PAD2) that binds to PAD2 in a target engagement assay (EC50 = 9.5 μM in HEK293/PAD2 cells).
CAS：2095107-57-4
分子式：C24H27FN6O3
分子量：466.5
纯度：98%
存储：Store at -20°C

Background:

CAY10723 is an inhibitor of protein arginine deiminase 2 (PAD2) that binds to PAD2 in a target engagement assay (EC50 = 9.5 μM in HEK293/PAD2 cells). It is 1.6-, 47-, and ~15-fold selective for PAD2 over PAD1, PAD3, and PAD4, respectively. CAY10723 inhibits histone H3 citrullination in HEK293/PAD2 cells (EC50 = 0.4 μM).