EGFR-IN-7 (compound 34) 是一种有效选择性的 EGFR 激酶抑制剂，对 EGFR (WT) 和 EGFR (mutant C797S/T790M/L858R) 的 IC50 值分别为 7.92 nM 和 0.218 nM，具有抗肿瘤活性，详细信息请参考专利 WO2019015655A1。
CAS：2267329-76-8
分子式：C32H41BrN9O2P
分子量：694.6
纯度：98%
存储：Store at -20°C

Background:

EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity[1]. EGFR (WT)|7.92 nM (IC50)|EGFR (C797S/T790M/L858R)|0.218 nM (IC50)

[1]. Aryl-phosphorus-oxygen compound as egfr kinase inhibitor.