Withanolide B is a withanolide that has been found in W.
CAS：56973-41-2
分子式：C28H38O5
分子量：454.6
纯度：98%
存储：Store at -20°C

Background:

Withanolide B is a withanolide that has been found in W. somnifera. Unlike withanolide A, it does not increase glucose uptake in L6 myotubes. In in silico docking studies, withanolide B was identified as a neuronal nitric oxide synthase (nNOS) inhibitor (Ki = 5.15 nM), that also inhibited inducible NOS (iNOS) and endothelial NOS (eNOS; Kis = 15.48 and 66.59 nM, respectively), and as a ligand for the PARP1 catalytic domain with an estimated Ki value of 7.54 nM.