生物活性
Hexestrol是一种致癌的合成雌激素，可抑制微管聚合和带状结构的形成。它是脂质过氧化的抑制剂。
靶点信息
| ERα | ERβ | | | |
| 0.07 nM(EC50) | 0.175 nM(EC50) | | | |
化学数据
| 目录号 | A10451 |
| 作用机制 | Agonist (激动剂) |
| M. Wt | 270.4 |
| Formula | C18H22O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 84-16-2 |
| Synonyms | Dihydrodiethylstilbestrol,Synthovo,Cycloestrol,Hormoestrol,Syntrogene |
| SMILES | CCC(C1=CC=C(C=C1)O)C(CC)C2=CC=C(C=C2)O |
溶解度
| In vitro (25°C) | DMSO | 37 mg/mL (136.85 mM) |
| Water | Insoluble |
| Ethanol | 37 mg/mL (136.85 mM) |
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 36.98 mL | 184.91 mL | 369.82 mL |
| 0.5 mM | 7.4 mL | 36.98 mL | 73.96 mL |
| 1 mM | 3.7 mL | 18.49 mL | 36.98 mL |
| 5 mM | 0.74 mL | 3.7 mL | 7.4 mL |
*The above data is based on the productmolecular weight 270.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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