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GSK1059615
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK1059615图片
CAS NO:958852-01-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品名称
GSK-1059615
产品介绍

生物活性

GSK1059615是PI3Kα (IC50 = 2 nM)的强效、可逆、ATP竞争性噻唑烷二酮抑制剂。

靶点信息

PI3KαPI3KβPI3KδPI3KγmTOR
0.4 nM0.6 nM2 nM5 nM12 nM

化学数据

目录号A10438
作用机制Inhibitor (抑制剂)
M. Wt333.4
FormulaC18H11N3O2S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.958852-01-2
SynonymsGSK-1059615
SMILESC1=CC2=NC=CC(=C2C=C1/C=C\3/C(=O)NC(=O)S3)C4=CC=NC=C4

溶解度

In vitroDMSO2 mg/mL (5.99 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM29.99 mL149.97 mL299.94 mL
0.5 mM6 mL29.99 mL59.99 mL
1 mM3 mL15 mL29.99 mL
5 mM0.6 mL3 mL6 mL

*The above data is based on the productmolecular weight 333.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.