您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Modipafant
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Modipafant
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:122957-06-6
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Modipafant is a potent dihydropyridine PAF (Platelet-Activating Factor) antagonist. PAF is an important inflammatory mediator in asthma. Modipafant is a lipophilic weak base with log D(octanol) 7.4 and pKa of 4.3 and 5.3 respectively. References: Jezequel SG, Uden S, Wastall P. Modipafant, a new PAF antagonist: pharmacokinetics and disposition in rat, dog and man. Xenobiotica. 1996 Sep;26(9):963-75. PubMed PMID: 8893043. 2: Kuitert LM, Angus RM, Barnes NC, Barnes PJ, Bone MF, Chung KF, Fairfax AJ, Higenbotham TW, O'Connor BJ, Piotrowska B, et al. Effect of a novel potent platelet-activating factor antagonist, modipafant, in clinical asthma. Am J Respir Crit Care Med. 1995 May;151(5):1331-5. PubMed PMID: 7735582.

纯度:≥98%

CAS:122957-06-6