您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Fulvestrant(Faslodex)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Fulvestrant(Faslodex)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fulvestrant(Faslodex)图片
CAS NO:129453-61-8
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
200mg电议
10mM * 1mL in DMSO电议

产品名称
ICI 182,780
ICI 182780
ICI182780
产品介绍

生物活性

Fulvestrant是一种雌激素受体拮抗剂,没有激动剂作用,它通过下调和降解雌激素受体发挥作用。

靶点信息

ER (Cell-free assay)
0.94 nM

化学数据

目录号A10410
作用机制Inhibitor (抑制剂)
M. Wt606.8
FormulaC32H47F5O3S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.129453-61-8
SynonymsICI 182,780 ; ICI 182780 ; ICI182780
SMILESC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F

溶解度

In vitro (25°C)DMSO88 mg/mL (145.02 mM)
WaterInsoluble
EthanolWarmed: 88 mg/mL (145.02 mM)
In vivo2% DMSO+30% PEG 300+2% Tween 80+ddH2O0.3 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM16.48 mL82.4 mL164.8 mL
0.5 mM3.3 mL16.48 mL32.96 mL
1 mM1.65 mL8.24 mL16.48 mL
5 mM0.33 mL1.65 mL3.3 mL

*The above data is based on the productmolecular weight 606.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.