生物活性
Formononetin (Formononetol)是来自黄芪根的植物雌激素和o-甲基化异黄酮。它被用作血液增强剂，并在补充和替代药物中改善血液微循环。它通过调节ERK1/2和p38 MAPK通路促进内皮修复和伤口愈合，这一过程涉及Egr-1转录因子的过度表达。
靶点信息
化学数据
| 目录号 | A10406 |
| M. Wt | 268.3 |
| Formula | C16H12O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 485-72-3 |
| Synonyms | Biochanin B, Formononetol, 7-Hydroxy-4'-methoxyisoflavone, 4'-O-methyldaidzein |
| SMILES | COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O |
溶解度
| In vitro | DMSO | 47 mg/mL (175.2 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 37.27 mL | 186.36 mL | 372.72 mL |
| 0.5 mM | 7.45 mL | 37.27 mL | 74.54 mL |
| 1 mM | 3.73 mL | 18.64 mL | 37.27 mL |
| 5 mM | 0.75 mL | 3.73 mL | 7.45 mL |
*The above data is based on the productmolecular weight 268.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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