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Exemestane
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Exemestane图片
CAS NO:107868-30-4
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
Aromasin
产品介绍

生物活性

Exemestane是一种口服类固醇芳香化酶抑制剂,除绝经后妇女的手术和/或放疗外,还用于ER阳性乳腺癌。

靶点信息

Aromatase (human)Aromatase (rat)
30 nM40 nM

化学数据

目录号A10378
作用机制Inhibitor (抑制剂)
M. Wt296.4
FormulaC20H24O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.107868-30-4
SynonymsAromasin
SMILESC[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=C)C4=CC(=O)C=C[C@]34C

溶解度

In vitroDMSO52 mg/mL (175.43 mM)
WaterInsoluble
Ethanol15 mg/mL (50.6 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM33.74 mL168.69 mL337.38 mL
0.5 mM6.75 mL33.74 mL67.48 mL
1 mM3.37 mL16.87 mL33.74 mL
5 mM0.67 mL3.37 mL6.75 mL

*The above data is based on the productmolecular weight 296.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.