您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Erlotinib HCl
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Erlotinib HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Erlotinib HCl图片
CAS NO:183319-69-9
包装与价格:
包装价格(元)
100mg电议
500mg电议

产品名称
CP-358774, OSI-774, NSC 718781
产品介绍

生物活性

Erlotinib hydrochloride是一种可逆的酪氨酸激酶抑制剂,作用于表皮生长因子受体(EGFR)。

靶点信息

HER1/EGFR (Cell-free assay)
2 nM

化学数据

目录号A10362
作用机制Inhibitor (抑制剂)
M. Wt429.9
FormulaC22H23N3O4.HCl
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.183319-69-9
SynonymsCP-358774, OSI-774, NSC 718781
SMILESCOCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl

溶解度

In vitro (25°C)DMSOWarmed: 4 mg/mL (9.3 mM)
WaterInsoluble
EthanolInsoluble
In vivo15% Captisol15 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.26 mL116.31 mL232.61 mL
0.5 mM4.65 mL23.26 mL46.52 mL
1 mM2.33 mL11.63 mL23.26 mL
5 mM0.47 mL2.33 mL4.65 mL

*The above data is based on the productmolecular weight 429.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.