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Epothilone B(EPO906)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Epothilone B(EPO906)图片
CAS NO:152044-54-7
包装与价格:
包装价格(元)
2mg电议
5mg电议
10mg电议
25mg电议
10mM * 1mL in DMSO电议

产品名称
Patupilone, Epothilone-B
产品介绍

生物活性

Epothilone B (EPO906)是一种紫杉醇样microtubule稳定剂。

靶点信息

Tubulin (Cell-free assay)
1.8 μM(EC0.01)

化学数据

目录号A10360
作用机制Inhibitor (抑制剂)
M. Wt507.7
FormulaC27H41NO6S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.152044-54-7
SynonymsPatupilone, Epothilone-B
SMILESC[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](OC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C

溶解度

In vitro (25°C)DMSO93 mg/mL (183.18 mM)
WaterInsoluble
Ethanol93 mg/mL (183.18 mM)
In vivo30% PEG400+0.5% Tween80+5% propylene glycol4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM19.7 mL98.48 mL196.97 mL
0.5 mM3.94 mL19.7 mL39.39 mL
1 mM1.97 mL9.85 mL19.7 mL
5 mM0.39 mL1.97 mL3.94 mL

*The above data is based on the productmolecular weight 507.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.