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LY317615(Enzastaurin)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LY317615(Enzastaurin)图片
CAS NO:170364-57-5
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
200mg电议
10mM * 1mL in DMSO电议

产品名称
LY-317615
产品介绍

生物活性

LY317615(Enzastaurin)是一种有效的,选择性的PKCβ抑制剂,具有抗增殖活性(IC50 =?6 nM)。

靶点信息

PKCβ (Cell-free assay)PKCα (Cell-free assay)PKCγ (Cell-free assay)PKCε (Cell-free assay)
6 nM39 nM83 nM110 nM

化学数据

目录号A10356
作用机制Inhibitor (抑制剂)
M. Wt515.6
FormulaC32H29N5O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.170364-57-5
SynonymsLY-317615
SMILESCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7

溶解度

In vitro (25°C)DMSO29 mg/mL (56.24 mM)
WaterInsoluble
EthanolInsoluble
In vivo15% Captisol28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM19.39 mL96.97 mL193.95 mL
0.5 mM3.88 mL19.39 mL38.79 mL
1 mM1.94 mL9.7 mL19.39 mL
5 mM0.39 mL1.94 mL3.88 mL

*The above data is based on the productmolecular weight 515.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.