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Donepezil hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Donepezil hydrochloride图片
CAS NO:120011-70-3
包装与价格:
包装价格(元)
25mg电议
100mg电议
200mg电议

产品介绍

生物活性

Donepezil hydrochloride是一种中枢可逆的乙酰胆碱酯酶抑制剂。

靶点信息

bAChEhAChE
8.12 nM11.6 nM

化学数据

目录号A10330
作用机制Inhibitor (抑制剂)
M. Wt416
FormulaC24H29NO3.HCl
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.120011-70-3
SMILESCOC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl

溶解度

In vitro (25°C)DMSOInsoluble
Water5 mg/mL (12.01 mM)
EthanolInsoluble
In vivo30% propylene glycol, 5% Tween 80, 65% D5W28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM24.04 mL120.19 mL240.38 mL
0.5 mM4.81 mL24.04 mL48.08 mL
1 mM2.4 mL12.02 mL24.04 mL
5 mM0.48 mL2.4 mL4.81 mL

*The above data is based on the productmolecular weight 416. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.