生物活性
Disulfiram是通过抑制乙醛脱氢酶来阻止体内酒精的加工，从而在消耗酒精时引起令人不快的反应。
靶点信息
化学数据
| 目录号 | A10320 |
| M. Wt | 296.54 |
| Formula | C10H20N2S4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 97-77-8 |
| SMILES | CCN(CC)C(=S)SSC(=S)N(CC)CC |
溶解度
| In vitro (25°C) | DMSO | 58 mg/mL (195.59 mM) |
| Water | Insoluble |
| Ethanol | 58 mg/mL |
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 2.3 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 33.72 mL | 168.61 mL | 337.22 mL |
| 0.5 mM | 6.74 mL | 33.72 mL | 67.44 mL |
| 1 mM | 3.37 mL | 16.86 mL | 33.72 mL |
| 5 mM | 0.67 mL | 3.37 mL | 6.74 mL |
*The above data is based on the productmolecular weight 296.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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