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Minocycline HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Minocycline HCl图片
CAS NO:13614-98-7
规格:98%
分子量:493.94
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
Tetracycline antibiotic
CAS:13614-98-7
分子式:C23H28ClN3O7
分子量:493.94
纯度:98%
存储:Store at -20°C

Background:

Minocycline hydrochloride is a broad-spectrum tetracycline antibiotic, acting by binding to the bacterial 30S ribosomal subunit and inhibiting protein synthesis.


参考文献:
[1]. Hu X, Wu B, Wang X, et al. Minocycline attenuates ischemia-induced ventricular arrhythmias in rats. Eur J Pharmacol. 2011 Mar 11;654(3):274-9.
[2]. Tao R, Kim SH, Honbo N, et al. Minocycline protects cardiac myocytes against simulated ischemia-reperfusion injury by inhibiting poly(ADP-ribose) polymerase-1. J Cardiovasc Pharmacol. 2010 Dec;56(6):659-68. doi: 10.1097/FJC.0b013e3181faeaf0.
[3]. Padi SS, Kulkarni SK. Minocycline prevents the development of neuropathic pain, but not acute pain: possible anti-inflammatory and antioxidant mechanisms. Eur J Pharmacol. 2008 Dec 28;601(1-3):79-87. doi: 10.1016/j.ejphar.2008.10.018.
[4]. Brundula V, Rewcastle NB, Metz LM, et al. Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis. Brain. 2002 Jun;125(Pt 6):1297-308.
[5]. Tikka T, Fiebich BL, Goldsteins G, et al. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci. 2001 Apr 15;21(8):2580-8.