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Dacarbazine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dacarbazine图片
CAS NO:4342-03-4
包装与价格:
包装价格(元)
100mg电议
200mg电议
500mg电议

产品名称
DTIC
产品介绍

生物活性

Dacarbazine是一种用于治疗各种癌症的抗肿瘤化学治疗药物。Dacarbazine是烷基化剂类别的成员,其通过向其DNA中添加烷基(CnH2n+1)来破坏癌细胞。

靶点信息

Nucleoside antimetabolite/analog

化学数据

目录号A10281
M. Wt182.18
FormulaC6H10N6O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.CAS: 4342-03-4
SynonymsDTIC
SMILESCN(C)N/N=C/1\C(=NC=N1)C(=O)N

溶解度

In vitro (25°C)DMSOWarmed: 12 mg/mL (65.86 mM)
WaterWarmed: 2 mg/mL (10.97 mM)
EthanolWarmed: 1 mg/mL (5.48 mM)
In vivo0.5% CMC Na28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM54.89 mL274.45 mL548.91 mL
0.5 mM10.98 mL54.89 mL109.78 mL
1 mM5.49 mL27.45 mL54.89 mL
5 mM1.1 mL5.49 mL10.98 mL

*The above data is based on the productmolecular weight 182.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.