您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > CYT997(Lexibulin)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
CYT997(Lexibulin)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CYT997(Lexibulin)图片
CAS NO:917111-44-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
CYT-997, Lexibulin
产品介绍

生物活性

CYT997 (Lexibulin)是一种新型的抗癌血管分裂剂(VDA)。在体外,CYT997被证明可有效抑制血管内皮生长因子刺激的人脐静脉内皮细胞(IC(50)3.7±1.8 nM)的增殖,并在100 nM时引起明显的形态变化,包括膜起泡。

靶点信息

Microtubules (cancer cell lines)
10 nM-100 nM

化学数据

目录号A10264
作用机制Inhibitor (抑制剂)
M. Wt434.5
FormulaC24H30N6O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.917111-44-5
SynonymsCYT-997, Lexibulin
SMILESCCC[C@@H](C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC

溶解度

In vitroDMSO77 mg/mL (177.2 mM)
WaterInsoluble
Ethanol18 mg/mL (41.42 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.01 mL115.07 mL230.15 mL
0.5 mM4.6 mL23.01 mL46.03 mL
1 mM2.3 mL11.51 mL23.01 mL
5 mM0.46 mL2.3 mL4.6 mL

*The above data is based on the productmolecular weight 434.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.