Cyclosporin A

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Cyclosporin A

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

59865-13-3

包装与价格：

包装	价格(元)
25mg	电议
100mg	电议
200mg	电议
10mM * 1mL in DMSO	电议

产品名称

Ciclosporin A, CsA, Ciclosporin, cyclosporine, cyclosporin,

产品介绍

生物活性

Cyclosporin A (Cyclosporine A)是一种免疫抑制剂，广泛用于异体后器官移植，以降低免疫系统的活性。

靶点信息

calcineurin (Cell-free assay)
7 nM

化学数据

目录号	A10260
M. Wt	1202.6
Formula	C62H111N11O12
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	59865-13-3
Synonyms	Ciclosporin A, CsA, Ciclosporin, cyclosporine, cyclosporin,
SMILES	CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

溶解度

In vitro (25°C)	DMSO	Warmed: 99 mg/mL (82.32 mM)
	Water	Insoluble
	Ethanol	Warmed: 99 mg/mL (82.32 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
<1 mg/ml means slightly soluble or insoluble. Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.32 mL	41.58 mL	83.15 mL
0.5 mM	1.66 mL	8.32 mL	16.63 mL
1 mM	0.83 mL	4.16 mL	8.32 mL
5 mM	0.17 mL	0.83 mL	1.66 mL

*The above data is based on the productmolecular weight 1202.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.