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Cladribine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cladribine图片
CAS NO:4291-63-8
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
200mg电议
10mM * 1mL in DMSO电议

产品名称
2-chlorodeoxyadenosine, Leustatin
产品介绍

生物活性

Cladribine是一种腺苷脱氨酶抑制剂,从而干扰细胞处理DNA的能力。

靶点信息

Adenosine deaminase (MM1.S cells)Adenosine deaminase (RPMI8226 cells)Adenosine deaminase (U266 cells)
0.18 μM0.75 μM2.43 μM

化学数据

目录号A10223
M. Wt285.7
FormulaC10H12ClN5O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.4291-63-8
Synonyms2-chlorodeoxyadenosine, Leustatin
SMILESC1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(N=C3N)Cl)CO)O

溶解度

In vitro (25°C)DMSO52 mg/mL (182.01 mM)
WaterInsoluble
EthanolInsoluble
In vivo5% DMSO+30% PEG 300+1% Tween 80+H2O9 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM35 mL175.01 mL350.02 mL
0.5 mM7 mL35 mL70 mL
1 mM3.5 mL17.5 mL35 mL
5 mM0.7 mL3.5 mL7 mL

*The above data is based on the productmolecular weight 285.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.