生物活性
Cidofovir (Vistide)通过选择性抑制病毒DNA的合成而抑制病毒复制。
化学数据
| 目录号 | A10214 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 279.2 |
| Formula | C8H14N3O6P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 113852-37-2 |
| Synonyms | Vistide |
| SMILES | C1=CN(C(=O)N=C1N)C[C@@H](CO)OCP(=O)(O)O |
溶解度
| In vitro | DMSO | 2 mg/mL (7.16 mM) |
| Water | 11 mg/mL (39.4 mM) |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 35.82 mL | 179.08 mL | 358.17 mL |
| 0.5 mM | 7.16 mL | 35.82 mL | 71.63 mL |
| 1 mM | 3.58 mL | 17.91 mL | 35.82 mL |
| 5 mM | 0.72 mL | 3.58 mL | 7.16 mL |
*The above data is based on the productmolecular weight 279.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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