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N-desethyl Amodiaquine(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-desethyl Amodiaquine(hydrochloride)图片
CAS NO:79049-30-2
规格:98%
分子量:400.7
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍

N-desethyl Amodiaquine is a primary metabolite of the antimalarial compound aminodiaquine, produced by the action of cytochrome P450 isoform 2C8.
CAS:79049-30-2
分子式:C18H18ClN3O.2HCl
分子量:400.7
纯度:98%
存储:Store at -20°C

Background:

N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

参考文献:
[1]. Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82.