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Celecoxib
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Celecoxib图片
CAS NO:169590-42-5
包装与价格:
包装价格(元)
100mg电议
500mg电议
1000mg电议
10mM * 1mL in DMSO电议

产品名称
Celebrex, Celebra
产品介绍

生物活性

Celecoxib是一种磺胺类非甾体抗炎药(NSAID)和选择性COX-2抑制剂,在Sf9细胞中IC50为40 nM。

靶点信息

COX-2 (Sf9 cells)
40 nM

化学数据

目录号A10193
作用机制Inhibitor (抑制剂)
M. Wt381.4
FormulaC17H14F3N3O2S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.169590-42-5
SynonymsCelebrex, Celebra
SMILESCC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F

溶解度

In vitro (25°C)DMSO65 mg/mL (170.44 mM)
WaterInsoluble
Ethanol28 mg/mL (73.42 mM)
In vivo2% DMSO+30% PEG 300+5% Tween 80+ddH2O4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.22 mL131.1 mL262.19 mL
0.5 mM5.24 mL26.22 mL52.44 mL
1 mM2.62 mL13.11 mL26.22 mL
5 mM0.52 mL2.62 mL5.24 mL

*The above data is based on the productmolecular weight 381.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.