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DMAPP(ammonium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DMAPP(ammonium salt)图片
CAS NO:1186-30-7
分子量:297.2

纯度:>95%

包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍

Dimethylallyl pyrophosphate and isopentyl pyrophosphate undergo condensation to yield geranyl pyrophosphate, which undergoes condensation with a second molecule of isopentyl pyrophosphate to yield farnesyl pyrophosphate.
CAS:1186-30-7
分子式:C5H12O7P2?3(NH4)

分子量:297.2

纯度:>95%
存储:Store at -20°C

Background:

Dimethylallyl pyrophosphate and isopentyl pyrophosphate undergo condensation to yield geranyl pyrophosphate, which undergoes condensation with a second molecule of isopentyl pyrophosphate to yield farnesyl pyrophosphate.[1] [2] Farnesylation is essential for the function of a number of proteins involved in signal transduction.[3][4]

Reference:
[1]. Barnard, G.F., and Popják, G. Human liver prenyltransferase and its characterization. Biochimica et Biophysica Acta 661, 87-99 (1981).
[2]. Laskovics, F.M., and Poulter, C.D. Prenyltransferase: Determination of the binding mechanism and individual kinetic constants for farnesylpyrophosphate synthetase by rapid quench and isotope partitioning experiments. Biochemistry 20, 1893-1901 (1981).
[3]. Hohl, R.J., Lewis, K.A., Cermak, D.M., et al. Stereochemistry-dependent inhibition of Ras farnesylation by farnesylphosphonic acids. Lipids 33, 39-46 (1998).
[4]. Rando, R.R. Chemical biology of protein isoprenylation/methylation. Biochimica et Biophysica Acta 1300, 5-16 (1996).