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Enniatin A1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Enniatin A1图片
CAS NO:4530-21-6
规格:98%
分子量:667.9
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Enniatins are cyclohexadepsipeptides commonly isolated from fungi that are known to have antibiotic properties and to induce apoptosis in several cancer lines.
CAS:4530-21-6
分子式:C35H61N3O9
分子量:667.9
纯度:98%
存储:Store at -20°C

Background:

Enniatins are cyclohexadepsipeptides commonly isolated from fungi that are known to have antibiotic properties and to induce apoptosis in several cancer lines. Many function as ionophores, forming pores in cellular membranes to allow selective ion transport. Enniatin A1 is one of four major analogs in the enniatin complex . Its ionophoric activity has been described. Additionally, enniatin A1 has been found to induce apoptosis in cancer cells (EC50 = 5 µM in H4IIE rat hepatoma cells), decreasing the activation of the cell proliferation kinase, ERK (p44/p42) and inhibiting TNF-α-induced NF-κB activation.