生物活性
Busulfan (Myleran,Busulfex)是烷基磺酸盐类中的细胞周期非特异性烷基化抗肿瘤药。
靶点信息
化学数据
| 目录号 | A10169 |
| M. Wt | 246.3 |
| Formula | C6H14O6S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 55-98-1 |
| Synonyms | Myleran, Busulfex, Busulphan |
| SMILES | CS(=O)(=O)OCCCCOS(=O)(=O)C |
溶解度
| In vitro (25°C) | DMSO | 43 mg/mL (174.58 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 40.6 mL | 203 mL | 406.01 mL |
| 0.5 mM | 8.12 mL | 40.6 mL | 81.2 mL |
| 1 mM | 4.06 mL | 20.3 mL | 40.6 mL |
| 5 mM | 0.81 mL | 4.06 mL | 8.12 mL |
*The above data is based on the productmolecular weight 246.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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