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Mepivacaine HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mepivacaine HCl图片
CAS NO:1722-62-9
包装:50mg
规格:98%
市场价:567元
分子量:282.81

产品介绍
local anesthetic
CAS:1722-62-9
分子式:C15H22N2O.HCl
分子量:282.81
纯度:98%
存储:Store at -20°C

Background:

Mepivacaine hydrochloride is a tertiary amine used as a local anesthetic. Target: Sodium Channel Mepivacaine hydrochloride is a local anesthetic of the amide type. Mepivacaine hydrochloride has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine). Mepivacaine hydrochloride is used in any infiltration and regional anesthesia. It is supplied as the hydrochloride salt of the racemate [1]. Mepivacaine hydrochloride displayed a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displayed a preference for TTXs Na(+) channels [2].
Reference:
[1]. Burm, A.G., et al., Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers. Anesth Analg, 1997. 84(1): p. 85-9.
[2]. Leffler, A., J. Reckzeh, and C. Nau, Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites. Eur J Pharmacol, 2010. 630(1-3): p. 19-28.