生物活性
Baicalin是已知的脯氨酰内肽酶抑制剂，并且影响GABA受体。
靶点信息
化学数据
| 目录号 | A10121 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 446.3 |
| Formula | C21H18O11 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 21967-41-9 |
| SMILES | C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O |
溶解度
| In vitro (25°C) | DMSO | 81 mg/mL (181.47 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
| In vivo | 5% DMSO+60% PEG 300+ddH2O | 14 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 22.41 mL | 112.03 mL | 224.06 mL |
| 0.5 mM | 4.48 mL | 22.41 mL | 44.81 mL |
| 1 mM | 2.24 mL | 11.2 mL | 22.41 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
*The above data is based on the productmolecular weight 446.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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