生物活性
Aztreonam (Azactam,Cayston)是一种合成的单环β-内酰胺抗生素 (一种单bactam)，其细胞核是基于一种从紫罗兰色杆菌中分离出来的更简单的单bactam。
化学数据
| 目录号 | A10118 |
| M. Wt | 435.4 |
| Formula | C13H17N5O8S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 78110-38-0 |
| Synonyms | Monobactam, SQ 26776, Squibb 26776 |
| SMILES | C[C@H]1[C@@H](C(=O)N1S(=O)(=O)O)NC(=O)/C(=N\OC(C)(C)C(=O)O)/C2=CSC(=N2)N |
溶解度
| In vitro | DMSO | 84 mg/mL (192.91 mM) |
| Water | 11 mg/mL (25.26 mM) |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 22.97 mL | 114.84 mL | 229.67 mL |
| 0.5 mM | 4.59 mL | 22.97 mL | 45.93 mL |
| 1 mM | 2.3 mL | 11.48 mL | 22.97 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.59 mL |
*The above data is based on the productmolecular weight 435.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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