生物活性
Azelastine HCl (Allergodil)是有效的第二代选择性组胺拮抗剂（组胺-H1-受体拮抗剂）。
靶点信息
化学数据
| 目录号 | A10117 |
| M. Wt | 418.4 |
| Formula | C22H24ClN3O.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 79307-93-0 |
| Synonyms | Allergodil,Rhinolast, Astelin, Optilas, Optivar |
| SMILES | CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl |
溶解度
| In vitro | DMSO | 27 mg/mL (64.53 mM) |
| Water | 78 mg/mL (186.42 mM) |
| Ethanol | 78 mg/mL (186.42 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 23.9 mL | 119.5 mL | 239.01 mL |
| 0.5 mM | 4.78 mL | 23.9 mL | 47.8 mL |
| 1 mM | 2.39 mL | 11.95 mL | 23.9 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
*The above data is based on the productmolecular weight 418.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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