CAS NO: | 2301916-69-6 |
规格: | 98% |
分子量: | 996.13 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
Background:
PROTAC FAK degrader 1 is a selective and potent focal adhesion kinase (Fak) degrader with an IC50 of 6.5 nM, DC50 of 3 nM[1]. IC50: 6.5 nM (Focal adhesion kinase)DC50: 3 nM (Focal adhesion kinase)[1]
[1]. Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.