生物活性
Atazanavir是一种氮杂肽及HIV-蛋白酶抑制剂,常与其他抗HIV药物结合,用于治疗HIV感染以及获得性免疫缺乏综合征。
靶点信息
化学数据
目录号 | A10097 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 704.9 |
Formula | C38H52N6O7 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 198904-31-3 |
Synonyms | Reyataz, BMS232632 |
SMILES | CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC |
溶解度
In vitro | DMSO | 62 mg/mL (87.95 mM) |
Water | Insoluble |
Ethanol | 28 mg/mL (39.72 mM) |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 14.19 mL | 70.93 mL | 141.86 mL |
0.5 mM | 2.84 mL | 14.19 mL | 28.37 mL |
1 mM | 1.42 mL | 7.09 mL | 14.19 mL |
5 mM | 0.28 mL | 1.42 mL | 2.84 mL |
*The above data is based on the productmolecular weight 704.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.