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AS703026(Pimasertib)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AS703026(Pimasertib)图片
CAS NO:1236699-92-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
AS-703026, MSC1936369B
产品介绍

生物活性

AS703026 (Pimasertib)是一种新型的,选择性的,口服可生物利用的MEK1/2抑制剂,可抑制MM细胞的生长和存活以及细胞因子诱导的破骨细胞分化。

化学数据

目录号A10089
作用机制Inhibitor (抑制剂)
M. Wt431.2
FormulaC15H15FIN3O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1236699-92-5
SynonymsAS-703026, MSC1936369B
SMILESC1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O

溶解度

In vitro (25°C)DMSO78 mg/mL (180.89 mM)
WaterInsoluble
EthanolInsoluble
In vivo0.5% CMC+0.25% Tween 8028 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.19 mL115.96 mL231.91 mL
0.5 mM4.64 mL23.19 mL46.38 mL
1 mM2.32 mL11.6 mL23.19 mL
5 mM0.46 mL2.32 mL4.64 mL

*The above data is based on the productmolecular weight 431.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.