生物活性
Apigenin是中央苯并二氮杂central受体的配体,其Ki为4μM竞争性抑制氟硝西epa的结合,发挥抗焦虑和轻微的镇静作用。
靶点信息
化学数据
目录号 | A10081 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 270.2 |
Formula | C15H10O5 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 520-36-5 |
Synonyms | 4’,5,7-trihydroxyflavone |
SMILES | C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O |
溶解度
In vitro | DMSO | 46 mg/mL (170.22 mM) |
Water | Insoluble |
Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 37.01 mL | 185.05 mL | 370.1 mL |
0.5 mM | 7.4 mL | 37.01 mL | 74.02 mL |
1 mM | 3.7 mL | 18.5 mL | 37.01 mL |
5 mM | 0.74 mL | 3.7 mL | 7.4 mL |
*The above data is based on the productmolecular weight 270.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.