生物活性
Amiloride HCl是一种Na+通道阻滞剂，还抑制TRPP3通道和Na+/H+交换剂（NHE）。
化学数据
| 目录号 | A10064 |
| 作用机制 | Blocker (阻断剂) |
| M. Wt | 266.1 |
| Formula | C6H9Cl2N7O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 2016-88-8 |
| Synonyms | MK 870, Midamor, Colectril, Amipramizide, Guanamprazine hydrochloride |
| SMILES | C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.Cl |
溶解度
| In vitro | DMSO | 49 mg/mL (184.15 mM) |
| Water | 6 mg/mL (22.54 mM) |
| Ethanol | 5 mg/mL (18.79 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 37.58 mL | 187.9 mL | 375.8 mL |
| 0.5 mM | 7.52 mL | 37.58 mL | 75.16 mL |
| 1 mM | 3.76 mL | 18.79 mL | 37.58 mL |
| 5 mM | 0.75 mL | 3.76 mL | 7.52 mL |
*The above data is based on the productmolecular weight 266.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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