生物活性
Aloin (Barbaloin)是一种从芦荟中得到的黄色结晶物质,据报道是酪氨酸酶的有效抑制剂。
靶点信息
化学数据
目录号 | A10058 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 418.4 |
Formula | C21H22O9 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 1415-73-2 |
Synonyms | Barbaloin |
SMILES | C1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(C=C3[C@@H]2[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)CO)O |
溶解度
In vitro | DMSO | 76 mg/mL (181.64 mM) |
Water | 76 mg/mL (181.64 mM) |
Ethanol | 2 mg/mL (4.78 mM) |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 23.9 mL | 119.5 mL | 239.01 mL |
0.5 mM | 4.78 mL | 23.9 mL | 47.8 mL |
1 mM | 2.39 mL | 11.95 mL | 23.9 mL |
5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
*The above data is based on the productmolecular weight 418.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.