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Tyrphostin AG 879
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tyrphostin AG 879图片
CAS NO:148741-30-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
AG879
产品介绍

生物活性

Tyrphostin AG 879是神经生长因子(NGF)TrkA酪氨酸激酶活性的抑制剂。

靶点信息

HER2-NeuTrkPDGFREGFR
1.0 μM10 μM>100 μM>500 μM

化学数据

目录号A10053
作用机制Inhibitor (抑制剂)
M. Wt316.5
FormulaC18H24N2OS
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.148741-30-4
SynonymsAG879
SMILESCC(C)(C)C1=CC(=C/C(=C(/N)\S)/C#N)C=C(C1=O)C(C)(C)C

溶解度

In vitro (25°C)DMSO35 mg/mL (110.59 mM)
WaterInsoluble
Ethanol3 mg/mL (9.47 mM)
In vivo1% DMSO+30% polyethylene glycol+1% Tween 8028 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM31.6 mL157.98 mL315.96 mL
0.5 mM6.32 mL31.6 mL63.19 mL
1 mM3.16 mL15.8 mL31.6 mL
5 mM0.63 mL3.16 mL6.32 mL

*The above data is based on the productmolecular weight 316.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.