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Fluorouracil(Adrucil)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fluorouracil(Adrucil)图片
CAS NO:51-21-8
包装与价格:
包装价格(元)
200mg电议
10mM * 1mL in DMSO电议

产品名称
Adrucil, 5-FU, Carac, Efudex, Fluoroplex
产品介绍

生物活性

Fluorouracil (Adrucil)是一种是DNA/RNA合成抑制剂,通过不可逆地抑制胸苷酸合酶起作用。

靶点信息

Thymidylate synthase (Tumor cells)

化学数据

目录号A10042
作用机制Inhibitor (抑制剂)
M. Wt130.1
FormulaC4H3FN2O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.51-21-8
SynonymsAdrucil, 5-FU, Carac, Efudex, Fluoroplex
SMILESC1=C(C(=O)NC(=O)N1)F

溶解度

In vitro (25°C)DMSO22 mg/mL (169.12 mM)
WaterInsoluble
EthanolInsoluble
In vivosaline (warming)9 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM76.86 mL384.32 mL768.64 mL
0.5 mM15.37 mL76.86 mL153.73 mL
1 mM7.69 mL38.43 mL76.86 mL
5 mM1.54 mL7.69 mL15.37 mL

*The above data is based on the productmolecular weight 130.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.