BODIPY-cholesterol is a biologically active and cell-permeable analog of cholesterol that is tagged with a fluorescent BODIPY group at carbon 24.
CAS：878557-19-8
分子式：C36H51BF2N2O
分子量：576.6
纯度：98%
存储：Store at -20°C

Background:

BODIPY-cholesterol is a biologically active and cell-permeable analog of cholesterol that is tagged with a fluorescent BODIPY group at carbon 24.[1],[2] It co-localizes with dehydroergosterol, a marker of cholesterol, in HeLa cells and is trafficked from the plasma membrane to the endocytic recycling compartment in BHK cells.2 BODIPY-cholesterol displays excitation/emission maxima of 480/508 nm, respectively, and has been used to monitor sterol uptake and inter-organelle sterol flux in cells.?

Reference：
1. Li, Z., Mintzer, E., and Bittman, R. First synthesis of free cholesterol-BODIPY conjugates. J. Org. Chem. 71(4), 1718-1721 (2006).
2. Wüstner, D., Solanko, L., Sokol, E., et al. Quantitative assessment of sterol traffic in living cells by dual labeling with dehydroergosterol and BODIPY-cholesterol. Chem. Phys. Lipids 164(3), 221-235 (2011).