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Protein Kinase C 19-31
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:121545-65-1
规格:98%
分子量:1543.82
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Protein Kinase C (19-31)是蛋白激酶 C (PKC)的抑制剂,是由 PKCa (残基 19-31) 伪底物调控域衍生而来,25 位丝氨酸取代野生型丙氨酸作为蛋白激酶 C 底物肽,用于检测蛋白激酶 C 的活性。Protein kinase C (PKC) 通过磷酸化丝氨酸和苏氨酸氨基酸残基上的羟基来调控其它蛋白的功能。
CAS:121545-65-1
分子式:C67H118N26O16
分子量:1543.82
纯度:98%
存储:Store at -20°C

Background:

Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins[1][2].




[1]. Mellor H, et al. The extended protein kinase C superfamily. Biochem J. 1998 Jun 1;332 ( Pt 2):281-92. [2]. Nishizuka Y (1995). Protein kinase C and lipid signaling for sustained cellular responses" (abstract). FASEB J. 9 (7): 484-96.