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BMPO
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BMPO图片
CAS NO:387334-31-8
规格:98%
分子量:199.2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
BMPO is a cyclic nitrone spin trap that can be used for the detection and characterization of thiyl radicals, hydroxyl radicals, and superoxide anions in vitro or in vivo.
CAS:387334-31-8
分子式:C10H17NO3
分子量:199.2
纯度:98%
存储:Store at -20°C

Background:

BMPO is a cyclic nitrone spin trap that can be used for the detection and characterization of thiyl radicals, hydroxyl radicals, and superoxide anions in vitro or in vivo. The BMPO-superoxide adduct does not rapidly decompose to the hydroxyl adduct in cells (t? = 23 min).[1][2] Also, the ESR spectrum of the BMPO-glutathionyl adduct does not fully overlap with the spectrum of its hydroxyl adduct. Purified by crystallization and stored as a solid, BMPO has a longer shelf life than liquid spin traps.[2]


Reference:
[1]. Zhao, H., Joseph, J., Zhang, H., et al. Synthesis and biochemical applications of a solid cyclic nitrone spin trap: A relatively superior trap for detecting superoxide anions and glutathiyl radicals. Free Radic. Biol. Med. 31(5), 599-606 (2001).
[2]. Khan, N., Wilmont, C.M., Rosen, G.M., et al. Spin traps: In vitro toxicity and stability of radical adducts. Free Radical Biology & Medicine 34(11), 1473-1481 (2003).