c-Fms-IN-8 (compound 4a)是 CSF-1R 的 2 型抑制剂，其IC50 值为9.1 nM。
CAS：1255303-58-2
分子式：C27H30N2O5
分子量：462.54
纯度：98%
存储：Store at -20°C

Background:

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1]. IC50: 9.1 nM (CSF-1R)[1].

[1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.