Licochalcone D 是存在于Glycyrrhiza inflate 中的黄酮类化合物，是NF-κB p65 的有效抑制剂。Licochalcone D 具有抗氧化、抗炎、抗癌等作用。
CAS：144506-15-0
分子式：C21H22O5
分子量：354.4
纯度：98%
存储：Store at -20°C

Background:

Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza inflate, is a potent inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2]. p65

[1]. Furusawa J, et al. Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol. 2009 Apr;9(4):499-507. [2]. Si L, et al. Licochalcone D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells. Oncol Rep. 2018 May;39(5):2160-2170.