Dapansutrile(OLT1177)是有效，选择性和有口服活性的NLRP3炎性小体抑制剂。具有抗炎，镇痛活性。
CAS：54863-37-5
分子式：C4H7NO2S
分子量：133.17
纯度：98%
存储：Store at -20°C

Background:

Dapansutrile (OLT1177) is a potent, selective and orally active inhibitor of NLRP3 inflammasome. Anti-inflammatory, analgesic activity[1]. NLRP3 inflammasome[1]

[1]. Toldo S, et al. The NLRP3 Inflammasome Inhibitor, OLT1177 (Dapansutrile), Reduces Infarct Size and Preserves Contractile Function After Ischemia Reperfusion Injury in the Mouse. J Cardiovasc Pharmacol. 2019 Apr;73(4):215-222.