CAS NO: | 1253452-78-6 |
规格: | 98% |
分子量: | 405.4 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Background:
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.IC50 value: 0.59( in Pheo A assay), 1.39 μM (in Hoechst 33342 assay).Target: BCRPThe more detailed information please refer to Compound 9 in the reference.
参考文献:
[1]. Pick A, et al. Specific inhibitors of the breast cancer resistance protein (BCRP). ChemMedChem. 2010 Sep 3;5(9):1498-505.