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Luteolin-7-rutinoside
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Luteolin-7-rutinoside图片
CAS NO:20633-84-5
包装:1mg
规格:98%
市场价:3236元
分子量:594.52

产品介绍
Luteolin-7-rutinoside 具有抗关节炎和抗真菌的双重作用,可用于治疗白色念珠菌感染引起的真菌关节炎。
CAS:20633-84-5
分子式:C27H30O15
分子量:594.52
纯度:98%
存储:Store at -20°C

Background:

Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.


At a dose of 10 μg Luteolin-7-rutinoside (lonicerin)/mL, there is an approximately 47% decrease of the proliferation as compared to proliferation of Luteolin-7-rutinoside treated (control) T cells (p<0.05). Luteolin-7-rutinoside at 40 μg/mL dose give almost the same rate of T cell proliferation as does 20 μg/mL dose of Luteolin-7-rutinoside. The suppressive activity is dose dependent. Luteolin-7-rutinoside treatment swifts Th1-Th2 balance away from Th1-toward Th2-type responses. Luteolin-7-rutinoside inhibits nitric oxide (NO) production from macrophages[1].



[1]. Lee JH, et al. Antiarthritic effect of lonicerin on Candida albicans arthritis in mice. Arch Pharm Res. 2011 May;34(5):853-9.