c-Fms-IN-10 是 [3,2-d] 噻吩并嘧啶的衍生物，FMS (集落刺激因子-1 受体，CSF-1R) 的激酶抑制剂，IC50 值为 2 nM。c-Fms-IN-10 具有抗肿瘤活性。
CAS：1527517-50-5
分子式：C22H19N7OS
分子量：429.5
纯度：98%
存储：Store at -20°C

Background:

c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, an kinase inhibitor of FMS (Colony stimulating factor-1 receptor, CSF-1R) with IC50 of 2 nM.c-Fms-IN-10 has anti-tumor activity[1].

[1]. Kim YY， et al. Synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel FMS inhibitors. Bioorg Med Chem Lett. 2019 Jan 15;29(2):271-275.