您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Temocapril HCl
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Temocapril HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Temocapril HCl图片
CAS NO:110221-44-8
规格:98%
分子量:513.07
包装与价格:
包装价格(元)
10mg电议
25mg电议

产品介绍
angiotensin-converting enzyme (ACE) inhibitor
CAS:110221-44-8
分子式:C23H28N2O5S2.HCl
分子量:513.07
纯度:98%
存储:Store at -20°C

Background:

Temocapril Hydrochloride is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. Target: ACETemocapril hydrochloride is a novel prodrug-type angiotensin-I converting enzyme (ACE) inhibitor, lowering of the dose of temocapril might be recommended only in patients with severe renal insufficiency [1]. Temocapril is regarded as an ACE inhibitor the disposition and efficacy of which are little affected in patients with impaired liver function [2].


参考文献:
[1]. Nakashima, M., et al., Pharmacokinetics of temocapril hydrochloride, a novel angiotensin converting enzyme inhibitor, in renal insufficiency. Eur J Clin Pharmacol, 1992. 43(6): p. 657-9.
[2]. Furuta, S., et al., Pharmacokinetics of temocapril, an ACE inhibitor with preferential biliary excretion, in patients with impaired liver function. Eur J Clin Pharmacol, 1993. 44(4): p. 383-5.