MRS 2500 tetraammonium salt is a highly potent and selective antagonist of the platelet P2Y1 receptor (Ki = 0.78 nM). MRS 2500 tetraammonium salt inhibits ADP-induced aggregation of human platelets with an IC50 of 0.95 nM. MRS 2500 tetraammonium salt inhibits the upregulation of NTPDase1 by ATPγS. References: Kwon SG, Roh DH, Yoon SY, Choi SR, Choi HS, Moon JY, Kang SY, Beitz AJ, Lee JH. Involvement of peripheral P2Y1 receptors and potential interaction with IL-1 receptors in IL-1β-induced thermal hypersensitivity in rats. Brain Res Bull. 2017 Jan 30;130:165-172. doi: 10.1016/j.brainresbull.2017.01.019. [Epub ahead of print] PubMed PMID: 28153540.

纯度：≥98%

CAS：630103-23-0