MPT0B002 is a microtubule inhibitor. It acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cell. References: Yeh YY, Liou JP, Lee YL, Lin JY, Huang HM. MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. Invest New Drugs. 2017 Aug;35(4):427-435. doi: 10.1007/s10637-017-0457-9. Epub 2017 Mar 27. PubMed PMID: 28349229.

纯度：≥98%

CAS：946077-08-3