MRS2365 is a highly potent and selective P2Y1 receptor agonist (EC50 = 0.4 nM). MRS2365 exhibits no activity at P2Y12 receptors and only very low agonist activity at P2Y13 receptors (at concentrations up to 1 μM). MRS2365 increases the upregulation of NTPDase1 by ATPγS. References: Mané N, Jiménez-Sábado V, Jiménez M. BPTU, an allosteric antagonist of P2Y1 receptor, blocks nerve mediated inhibitory neuromuscular responses in the gastrointestinal tract of rodents. Neuropharmacology. 2016 Nov;110(Pt A):376-85. doi: 10.1016/j.neuropharm.2016.07.033. Epub 2016 Aug 3. PubMed PMID: 27496690.

纯度：≥98%

CAS：436847-09-5